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Ahead of the 18–19 March RAWG, Technical Committee and Steering Committee meetings, this update highlights when article thresholds and notification triggers may apply. ECHA has added n-hexane (EC 203-777-6; CAS 110-54-3) to the REACH Candidate List of substances of very high concern (SVHC), based on concerns relating to specific target organ toxicity after repeated exposure (human health).